in two or three years much of the united states, the united kingdom and other countries' populations will be on ketamine or ketamine-like compound medications as treatment for depression and likely a number of other diagnoses that will branch out and take over like a bad case of black mold. johnson & johnson and other companies have been pushing ketamine and drugs with similar action through trials as fast as they can:

ketamine has been shown to have a clinically effective, multi-day antidepressant effect that outlasts its disassociative effects but not its potential for addiction. johnson & johnson are aiming to hit the market in 2017 with a medication for major depressive cases resistant to treatment. this is a just a bottle of esketamine moms will spray up their noses after using other useful, reliable johnson & johnson products to sanitize their full quiver, however the entire market may have its legs knocked out from under it by a paper in nature


that identifies the (2R,6R)-HNK metabolite as the antidepressant aspect of the drug, which "lacks ketamine-related side effects". so expect all of your surviving friends & family to be in the kiddie pool version of the K hole until death. personally i'm glad for all this because it means we'll for sure get an adam curtis documentary.
Thanks but I'll stick to meow meow
Meow meow whats for lunch lol
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tpaine posted:

EmanuelaBrolandi posted:

Thanks but I'll stick to meow meow

*purrs and rubs up against you seductively*

urgh why do the dames always go 4 the fuckboys and not the nice guys wit baggy jeans like me

I was talking about the drug but also yes me and goatstein are into cats and I def do think about that when I do the meow meow at the club and listen to jungliist music

Sort of like aerdil thinking of deaden while having sex w a woman in public on cocaine but w meow meow and cats
i'm starting to advocate avoiding legal drugs entirely
like, is there some dark hall with King Pharma lounging on a throne, who decides that nothing they've got can compete with legal pot so they need to start selling opoids, antipsychotics, and special k to keep the dollars rolling? or is it more some lawyer realizes the industry is so powerful nobody can stop them so why not get rich as fuck ruining millions of lives
theyre figuring out how to maneuver against big ag's cut in the weed trade. monsanto owns the patent to skunk up in canada so

Edited by shriekingviolet ()

god phoneposting is wretched

Urbandale posted:

theyre figuring out how to maneuver against big ag's cut in the weed trade. monsanto owns the patent to skunk up in canada so

No they fucking don't. Seriously? I'm not going to google this, so you'd better be on the level with this.

Edited by winebaby ()


camera_obscura posted:

not going to google this, so you'd better be on the level


naw its just a popular myth. theyve just been talking about weed a lot in the past five years or so.


To the OP, a black man representing himself on the internet with his blackness: I will not be on ketamine soon. The only drug that goes into my system is success.
I look forward to the thread in 9 years where everyones like im damn glad all these crackers got addicted to ketamine and killed theyselves, I'm a marxist and that means I think its good when working class people die.
All the medical companies are owned by aig finance ppl from kkkevens adoptive home of alaska down to Puerto Rico

Keven posted:

I look forward to the thread in 9 years where everyones like im damn glad all these crackers got addicted to ketamine and killed theyselves, I'm a marxist and that means I think its good when working class people die.

That's me today


Keven posted:

I look forward to the thread in 9 years where everyones like im damn glad all these crackers got addicted to ketamine and killed theyselves, I'm a marxist and that means I think its good when working class people die.

is this a weak ironic racism post or is it a weak marxier than thou post

Perhaps I'll discuss it with you, if you were willing to engage in good faith. However, you are not. Much like how you gained admin ship on this forum, you're attempting to sneak insults in the back door, under cover of night.
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I agree that what Doctor What did to this forum could be considered a kind of violation. However, the state would never agree to prosecute it as rape. Once again, I am brought to an unfortunate but inevitable conclusion: cyclone boy was right.
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i thought cycloneboy was alright
Ketamine while a great drug is highly addictive and basically rots your bladder if you use it long term.
The Uk's Secret Ketamine Epidemic

My ex was more than a casual user of ketamine and it also prevented him from getting hard ons true story but with the recent revelations of millennials having less sex maybe this is overall a good thing in late capitalism.....

Ketamine gains favor to treat chronic pain, depression
Karen Bouffard, The Detroit News 10:50 p.m. EDT October 16, 2016

Troy McLaughlin said ketamine treatment for his severe depression at Michigan Progressive Health in Royal Oak saved his life.
(Photo: Robin Buckson / The Detroit News)

The 1990s-era club drug nicknamed “Special K,” or ketamine, is gaining interest in Michigan and across the country as a potent treatment for chronic pain and severe depression, spurring calls for standards to regulate its use.

Michigan Progressive Health Inc. in Royal Oak is among the first clinics nationally to offer ketamine infusion therapy for patients whose conditions have not responded to traditional therapies. Since opening in April, the clinic has attracted patients from as far as the Upper Peninsula and Florida.

The therapy is also available from a small number of doctors who administer intravenous ketamine at their offices alongside more traditional treatments. One Dearborn anesthesiologist uses ketamine to treat complex regional pain syndrome, an excruciating and often intractable condition.

A University of Michigan psychiatrist has used ketamine to treat major depressive disorder and is set to begin clinical trials to study how it works.

“For many conditions, it works in half to two-thirds of patients,” said Dr. Sagar Parikh, the John F. Greden professor of depression and clinical neuroscience at the University of Michigan.

Despite its controversial past, law enforcement agencies have not objected to ketamine treatment.

Tuscola County Prosecutor Mark Reene, president of the Prosecuting Attorneys Association of Michigan, said “we expect and trust the medical community prescribes a substance such as ketamine appropriately.”

Studies have shown that low doses of ketamine, given intravenously over several hours, can bring nearly immediate relief to patients with severe depression and some forms of chronic pain. But the treatments are not approved by the federal Food and Drug Administration or covered by health insurance.

Supporters say most doctors who offer ketamine therapy are following protocols that have been tested in clinical trials and published in respected scientific journals. But a few bad actors have exploited the growing demand for the drug, said Dennis Hartman, executive director and founder of the Seattle-based Ketamine Advocacy Network that lists 19 sites across the country, mostly in major cities such as Boston and Los Angeles.


“(Some doctors) are doing it in ways that are easy and fast for them but not necessarily best for the patient,” Hartman said, adding that some psychiatrists have administered ketamine by intramuscular injection rather than intravenously — a method of delivery that has not been vetted in clinical trials.

The Ketamine Advocacy Network was formed by four patients with depression who benefited from ketamine as participants in a clinical trial funded by the National Institute of Mental Health in Bethesda, Maryland.

“To have experienced such sudden, profound relief, we couldn’t ignore the need to increase access (to ketamine treatment),” Hartman said.

The network soon will roll out standards developed with leading research institutions, including Yale University.

“We need to validate a standard of care,” Hartman said. “There is no professional organization made up of trained medical professionals who have set standards. We’re patients, we’re not experts. ... But since they’re not doing it we will do it.”

Worthwhile expense

Standards are needed not only to protect patients’ safety but to satisfy insurance carriers that consider the treatments experimental.

The vast majority of health insurers do not cover the treatment, but resistance may be softening. California-based Kaiser Permanente has launched a pilot project offering ketamine coverage to some members.

“The pilot program is in Northern California at a few sites at this point in time,” Kaiser spokeswoman Diana Yee said, noting the company doesn’t operate in Michigan.

Treatments typically cost $400 to $1,500 per treatment out of pocket, depending on the patient’s condition. Infusions can take from one hour to six hours and should be supervised by a physician.

An initial treatment can involve twice weekly infusions for as many as six weeks. Once in remission, patients need to return for a booster every six weeks to two months to maintain relief from their symptoms.

For Troy McLaughlin, 40, of Adrian, it was a worthwhile expense. His severe depression was triggered by his brother’s death in a 2013 plane crash. His first ketamine treatment at Michigan Progressive Health in Royal Oak brought nearly immediate relief, McLaughlin said. He recently completed an initial course of six treatments and says “it saved my life.”

“The final decision for me was ‘this course of treatment is about $4,000 and a funeral’s about $4,000’— that’s honestly how bad I felt,” McLaughlin said.

“With the depression, the mind is just beating you up all the time. It’s impending doom. (Ketamine) stops all that. The sad thoughts or depressive thoughts go away.”

Ketamine is an anesthetic that’s a staple in hospital emergency departments, on battlefields and in veterinary offices, said Dr. Megan Oxley, an emergency physician and founder of Michigan Progressive Health.

It’s a Schedule III drug, meaning ketamine’s potential for abuse is lower than than drugs like heroin or cocaine. It’s classified as a “dissociative anesthetic” because it makes people feel disconnected from their environment. It can also cause hallucinations.

Illicit users take ketamine in massive doses to get very high and then pass out, Oxley said. Therapeutic doses are extremely small and administered slowly.

During a recent treatment, Oxley checked on her patient every five to 10 minutes. She said she checks their vital signs, makes sure they’re comfortable and not experiencing anxiety, which can be a side effect.

McLaughlin, the patient from Adrian, said his treatments initially caused anxiety, so Oxley reduced his dose slightly and added more time between treatments.

“You feel dissociated from your body, (but) I know I’m in a safe environment,” McLaughlin said. “By the time you’re home you can function, but you’re tired for the rest of the day.”

Break the cycle

Wesley Cooper, 31, of Royal Oak, has suffered from severe chronic pain since breaking his back in a snowboarding accident at the age of 21.

He’s taken medication for depression, a common problem for chronic pain patients. And he said he’s tried “every narcotic known to man” to cope with his unrelenting pain.

Cooper gave up both the antidepressants and the opioids after ketamine treatments from his pain doctor, Dearborn anesthesiologist Dr. Hussein Huraibi.

“I did six to eight treatments over a two-week period and then I came off my pain meds altogether,” Cooper said. “My nerve pain was gone.”

Huraibi said he began offering ketamine treatments about three years ago. About two-thirds of patients benefit from the treatment, said Huraibi, who added he first learned about it during residency training at Yale University.

“If we can break the cycle in some way,” he said, “it would help get these people back on their feet.”

UM’s Parikh is months away from starting a large, multi-site clinical trial of ketamine.

Funded with $1 million from a private donor, Parikh’s team will search for biomarkers or indicators to show when patients are responding to ketamine treatment for depression.

Such discoveries could lead to the development of a blood test that could predict who will benefit from ketamine treatment.

The lack of FDA approval, usually a prerequisite for insurance coverage, is “the elephant in the room,” he said.

Getting FDA approval can cost millions of dollars, typically paid by a pharmaceutical company that holds a patent on a drug. Ketamine is generic, so no drug company stands to benefit from FDA approval of ketamine infusion. Efforts are underway to develop other forms of ketamine, such as a nasal spray, that could be proprietary.

“If a new use of (ketamine) comes along and it enters into standard treatments, than insurance companies should be willing to pay for it,” Parikh said.

was wondering if the experimental moneymaker types at places like UMich were going to hold off until they could start human trials of drugs based on the findings about the non-addictive metabolite. but no they're just going to go ahead and get depressed people hooked on an addictive anesthetic so they'll have to change medications and pay name brand prices for the non-addictive stuff if it ever displaces what exists. which will be considered good for patients and touted as how the free market brings Progress.

i'm interested to know more about the Ketamine Advocacy Network and its "four patients".
So this is just a repeat of the push to prescribe oxycodone in the 90s, right?
no? that doesn't make sense at all
What I meant was they are going to begin pushing doctors to prescribe an easily abusable medication even in cases where it isn't necessary. People will begin taking it to get high or sell it instead of as prescribed forcing them to get more any way they can. The companies know this and don't care because making ketamine more widely available will also raise its demand.
i know we all miss sam very dearly but i dont think this is going to lure him back
"will be", he says. Get a loada this fukkin guy with his future tense lmao
man people were all already on ketamine in like 2004
can one not post in jest on the rhizzone anymore
I saw a guy dousing himself in isopropyl alcohol on the bus once, perhaps a cooling effect??
everything happening has already happened and is known by all especially things people would have mentioned half a year ago when they posted in this thread if that were true

drwhat posted:

can one not post in jest on the rhizzone anymore

what is the joke. the height of recreational ketamine use was years before 2004, something about which i know nothing.

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