#41

cars posted:

drwhat posted:
can one not post in jest on the rhizzone anymore


what is the joke. the height of recreational ketamine use was years before 2004, something about which i know nothing.


the joke is creating the character of someone so naive, spoiled, and self-centred that they evaluate the world only through fads of recreational drug use, and so therefore your post about something serious is in his eyes not serious at all because you are behind the times, not that he even really knows what the times are, and basically lives in a haze of narcisstic bullshit with his shitty ignorant friends. so you laugh at the idea of that character while we reassure each other, with the shared laughter, that this character is funny to us because that perspective is obviously absurd and we hate this type of person. this is what i call ironic forum posting

never mind i'll go to the election thread, thanks for your informative op

#42
#43
#44
#45
I treated my alcohol addition by not drinking alcohol anymore, which I understand has a low success rate. So treating your alcohol addiction via ketimine addiction seems reasonable.
#46
Doesn't ketimine also completely fuck up your liver and kidneys that seems like a bad idea
#47
this guy i know kept trying to make me do lines of what he called calvin klein, or coke and ketamine. i honestly might have tried it if he hadnt been trying to force it on me like the undercoating on a used car that he was dying to see me drive off the lot in that very day
#48
^^^ that sounds like the worst drug combination ever

Keven posted:

Doesn't ketimine also completely fuck up your liver and kidneys that seems like a bad idea


there's renal toxicity associated with chronic abuse, would be unheard of following a single use treatment, and its hepatoxicity is absolutely minimal even with chronic abuse. it's also pretty hard to get addicted to since it necessitates being a numbed up idiot robot person for extended periods of time and consistent access to the drug, combined with its not being even close to as reinforcing as stimulants or opiates.

the main problem would be people relapsing after a week or it just not being effective in the first place; it'd be useless without doing normal rehab shit along with it

#49
the use for chronic depression mentioned in detail on the first page probably carries more of those risks. it's why i was curious whether pharma companies were going to chase down a sound delivery method for the isolated metabolite, test it, etc. to avoid social censure over the drug's reputation. but of course they aren't and are instead working to reinvent ketamine as a miracle drug in the press, because there are enough existing ketamine compounds out there already that they can start selling for these purposes now after minimal testing for efficacy, kind of like how they were able to sell a bunch of old, shelved anti-seizure medications again based on shaky psychiatric applications a few years ago.

this massive single dose to treat alcoholism thing seems more like part of that press push, a solution in search of an existing problem, unless they are planning on having people self-dose in a bathtub full of water and the idea is to literally murder alcoholics which doesn't seem likely.
#50
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#51
god if that won't bring tpaine back nothing will
#52
don't do meth, which is not the same as amphetamine salts.
#53
Do meth if you want to. Don't let people boss you about
#54
the people's revolution lies at the end of a road of crushed up crystals. what substances those crystals contain is up to you, my friends.
#55
actually do listen to me, and don't do meth because you can't get adderall.
#56
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#57
i was going to reply with a joke but cars' avatar talked me out of it. i hope things get get better for you, comrade.
#58
yeah i've just actually seen people self medicate with meth because of the part of the country i come from and the results as they used to say, v. bad.
#59
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#60
Me also, I have the ADHD a.k.a. moral failure to meta-program my fucked up brain which is the root cause of all my other failures. Ketamine is good, lamotrigine is good also.
#61
sucking is normal though
#62

camera_obscura posted:

sucking is normal though


No

#63
what about tianeptine or phenibut? i've heard mixed reviews but purchase isn't exactly straight forward
#64
read some great things about phenazepam
#65

groundservices posted:

I think they pegged me as a drug seeker at the free clinic cuz I was smoking a lot of weed

first rule of getting adequate mental health treatment is never admit to any recreational drug use

#66
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#67

TG posted:

what he called calvin klein, or coke and ketamine



lmao

#68

chickeon posted:

first rule of getting adequate mental health treatment is never admit to any recreational drug use



100%. if you show up and apply for disability in the U.S. with a letter from the Surgeon General saying you're a paranoid schizophrenic and then mention you need treatment for substance abuse problems you will be auto-binned.

#69
A friend told me that someone they know was doing a 6 month inpatient clinical trial for ketamine as treatment for treatment-resistant depression and my first reaction was that I also want to be in the hospital for 6 months. But I'm better now
#70
thanks for the heartwarming reminder that as bad as my medical problems might be, they'd be a thousand times worse if i lived in the simmering hellhole that is the US

i was still fucked over once for "drug seeking behaviour" despite repeatedly specifying that I want painkillers that aren't opiates. some doctors are great evidence that education doesn't make you smarter
#71

shriekingviolet posted:

some doctors are great evidence that education doesn't make you smarter



this is my lived experience every god damned day. the only difference between a doctor and any jagoff from the street is doctors are possessed of an inhuman streak of self-denial that allowed them to get through the miserable, decade-long grind that is medical education

#72
i bounced across 5 different doctors and specialists over a couple years who gave me an endless procession completely ineffective prescriptions and increasingly baroque tests, i was under the impression that i had some untreatable esoteric fringe disorder

finally i went to another new guy who, right in front of me, looks up "cluster headache" on fucking wikipedia, sees in the opening paragraphs that triptans are a recommended treatment.

"did any of your doctors try any kind of triptan?" "no" "well let's try that"

now i take sumatriptan and it works. but i'll never get back those years of pointless agony that incompetent rich pricks cost me!!
#73
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#74
Haha yes, reminds me of when I was getting (what I concluded were) cluster headaches, then when I went to a doctor (again) made sure to emphasize the symptoms that differentiate them from other kinds of headaches so that he could use his expertise to conclude that I had cluster headaches. Always do your own research!
That's especially true for psychiatric meds, by the way. I've had multiple experiences of being told I couldn't actually be having whatever side effect I was in fact having because they'd never heard of that happening.
#75

cars posted:

the use for chronic depression mentioned in detail on the first page probably carries more of those risks. it's why i was curious whether pharma companies were going to chase down a sound delivery method for the isolated metabolite, test it, etc. to avoid social censure over the drug's reputation. but of course they aren't and are instead working to reinvent ketamine as a miracle drug in the press, because there are enough existing ketamine compounds out there already that they can start selling for these purposes now after minimal testing for efficacy, kind of like how they were able to sell a bunch of old, shelved anti-seizure medications again based on shaky psychiatric applications a few years ago.

this massive single dose to treat alcoholism thing seems more like part of that press push, a solution in search of an existing problem, unless they are planning on having people self-dose in a bathtub full of water and the idea is to literally murder alcoholics which doesn't seem likely.



those ketamine manufacturing plants cost a billion bucks, easy. they don't wanna build a new clinical plant for hundreds of millions, wait 10+ years for clinical to come back, then spend another billion on the production plant.

i briefly worked at a pharma plant that made around 2 lbs of product per year, sold it for $1.2 billion. huge money maker. i got talking to a consultant guy who did marketing for the drug, and their #1 marketing strategy was to target pediatricians (read: young children), because at that age the body adapts to the drug at the expense of competitors'. so you snag a lifelong customer that needs the drug to survive.

#76

toyotathon posted:

i briefly worked at a pharma plant that made around 2 lbs of product per year, sold it for $1.2 billion. huge money maker. i got talking to a consultant guy who did marketing for the drug, and their #1 marketing strategy was to target pediatricians (read: young children), because at that age the body adapts to the drug at the expense of competitors'. so you snag a lifelong customer that needs the drug to survive.



#77

shriekingviolet posted:

finally i went to another new guy who, right in front of me, looks up "cluster headache" on fucking wikipedia



Why had you not looked it up on the internet yourself?

#78

toyotathon posted:

i briefly worked at a pharma plant that made around 2 lbs of product per year, sold it for $1.2 billion. huge money maker. i got talking to a consultant guy who did marketing for the drug, and their #1 marketing strategy was to target pediatricians (read: young children), because at that age the body adapts to the drug at the expense of competitors'. so you snag a lifelong customer that needs the drug to survive.



what drug is this

#79

toyotathon posted:

those ketamine manufacturing plants cost a billion bucks, easy. they don't wanna build a new clinical plant for hundreds of millions, wait 10+ years for clinical to come back, then spend another billion on the production plant.

i briefly worked at a pharma plant that made around 2 lbs of product per year, sold it for $1.2 billion. huge money maker. i got talking to a consultant guy who did marketing for the drug, and their #1 marketing strategy was to target pediatricians (read: young children), because at that age the body adapts to the drug at the expense of competitors'. so you snag a lifelong customer that needs the drug to survive.



yeah, curious to know what drug that was or at least what class? that doesn't really square w/ my knowledge of pharmacology. the body doesn't really "adapt" to different drugs at the expense of others afaik but whatever i'm just an ass-wiper

#80
When you're talking about psychopharmaceuticals the adaptation can be a physical deficiency in the neurotransmitter (because the brain is affected during formative growth) or just a lifelong feeling that the mental state under the drug is the true normal.