Gssh posted:kratom is a strange one, quite a few poorly understood alkaloids hitting not just opiod receptor but noradrenergic and serotonergic pathwasys also. too many potentially bad interactions for my liking. like theres been numerous reports of seizures in combination with modafinil, but no real understanding of why.
one explanation is that several batches were shown to contain O-desmethyl tramadol (added because it has an effect profile similar to kratom alkaloids (including norepinephrine and serotonin reuptake inhibition)) which like tramadol probably lowers the seizure treshold (unlike kratom alkaloids and most opiates)
Edited by Gssh ()
It's really hard to tell if and when it's working and hard to figure out a dose.
The internet Kratom community is filled with conflicting evidence. Some people claim different strains give you completely different effects, some people claim smaller doses are more intense than larger ones. I saw one guy claiming anxiety is caused by poor-functioning kidneys...
I was really excited that I had found something other than a Benzo or an antidepressant to help with my anxiety but now I'm afraid this confusing ass plant is going to be impossible to use safely and effectively.
a) where did it come from, in the west? does its popularity have anything to do with the opioid crisis?
b) who the fuck decided it was a good idea to chug ass powder
winebaby posted:a lot of people who would otherwise use heroin seem to be buying/using it in my area, a development that is probably good for them imo
winebaby posted:a lot of people who would otherwise use heroin seem to be buying/using it in my area, a development that is probably good for them imo
they're gonna ban it